In one study, pre-targeting was conducted utilizing streptavidin-[genetically engineered fusion protein] molecules followed by radiolabeled biotin in nine patients with metastatic colorectal cancer. The demonstrated radiation dosage ratios were 139:1 tumor-to-marrow and 56:1 tumor-to-whole body, with no blood, liver, or kidney toxicity.35
Disclaimer: This website is not intended to replace professional consultation, diagnosis, or treatment by a licensed physician. If you require any medical related advice, contact your physician promptly. Information at Biotin.com is exclusively of a general reference nature. Do not disregard medical advice or delay treatment as a result of accessing information at this site.
The bacterial counterpart to avidin.35